View or download helpful AHP-Related resources

Educational materials and resources have been created to provide you with a deeper understanding of acute hepatic porphyria (AHP). These resources will help you identify, diagnose, and manage your patients with this debilitating disease.

This series of learning modules lays the groundwork for understanding porphyria, recognizing symptoms, and gaining insight into how it affects your patients. Modules can be viewed online and/or downloaded as PDFs.

Classification of acute hepatic porphyria

Module 01:
Classification of
Porphyria

Classification of acute hepatic porphyria

Module 1 Reviews:

  • 2 major categories of the rare genetic diseases classified as porphyria—
    acute hepatic porphyria and photocutaneous porphyria
  • The heme biosynthesis pathway
  • The prevalence of the most common AHP
  • Precipitating factors of acute exacerbations
Pathophysiology of acute hepatic porphyria

Module 02:
Pathophysiology of Acute Hepatic Porphyria (AHP)

Pathophysiology of acute hepatic porphyria

Module 2 Reviews:

  • The pathophysiology of AHP
  • How exacerbations and, for some patients, chronic symptoms are associated with widespread neurologic lesions, leading to dysfunction across the autonomic, central, and peripheral nervous systems
  • The clinical evidence for the role of ALA (aminolevulinic acid) and PBG (porphobilinogen) in AHP exacerbations
Simplifying the diagnostic path of acute hepatic porphyria

Module 03:
Acute Hepatic Porphyria (AHP): Simplifying the Diagnostic Path

Simplifying the diagnostic path of acute hepatic porphyria

Module 3 Reviews:

  • The diagnostic challenges of AHP
  • Common AHP symptoms
  • How and why AHP can be easily misdiagnosed
  • The biochemical diagnosis of AHP
  • Genetic testing as a confirmatory method
Patient burden of acute hepatic porphyria

Module 04:
The Patient Burden of Acute Hepatic Porphyria (AHP)

Patient burden of acute hepatic porphyria

Module 4 Reviews:

  • The clinical and lifestyle burden of AHP
  • Challenges with diagnosis
  • The debilitating physical and emotional effects AHP has on patients’ daily functioning
Acute hepatic porphyria diagnosing and testing handout

AHP Diagnosis and
Testing Handout

Acute hepatic porphyria diagnosing and testing handout

This helpful flyer summarizes:

  • What AHP is
  • The signs and symptoms
  • Misdiagnosis
  • What to test for with spot urine tests
  • Consequences of delayed diagnosis

Access Additional Resources

For more information about AHP and other forms of porphyria, please visit American Porphyria Foundation and The Porphyrias Consortium. These organizations are dedicated to helping healthcare providers, patients, and their caregivers understand porphyria.

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