View or download helpful AHP-Related resources

Educational materials and resources have been created to provide you with a comprehensive understanding of acute hepatic porphyria (AHP). These resources will help provide additional education on identification, diagnosis and management of patients with this debilitating disease.

AHP Interactive Case Study

AHP INTERACTIVE CASE STUDY Reviews:

  • A hypothetical case of a patient with AHP
  • Identifying the signs and symptoms of AHP
  • Tests & assessments leading to diagnosis
Acute hepatic porphyria interactive case study
 

This series of learning modules lays the groundwork for understanding acute hepatic porphyria, recognizing symptoms, and gaining insight into how it may affect your patients. Modules can be viewed online and/or downloaded as PDFs.

Classification of acute hepatic porphyria

Module 01:
Classification of
Porphyria

Classification of acute hepatic porphyria
 

Module 1 Reviews:

  • 2 major categories of the rare genetic diseases classified as porphyria—acute hepatic porphyria and photocutaneous porphyria
  • The heme biosynthesis pathway
  • The prevalence of the most common AHP
  • Precipitating factors of acute attacks
 
Pathophysiology of acute hepatic porphyria

Module 02:
Pathophysiology of Acute Hepatic Porphyria (AHP)

Pathophysiology of acute hepatic porphyria
 

Module 2 Reviews:

  • The pathophysiology of AHP
  • How attacks and, for some patients, chronic symptoms are associated with widespread neurologic lesions, leading to dysfunction across the autonomic, central, and peripheral nervous systems
  • The clinical evidence for the role of ALA (aminolevulinic acid) and PBG (porphobilinogen) in AHP attacks
 
Simplifying the diagnostic path of acute hepatic porphyria

Module 03:
Acute Hepatic Porphyria (AHP): Simplifying the Diagnostic Path

Simplifying the diagnostic path of acute hepatic porphyria
 

Module 3 Reviews:

  • The diagnostic challenges of AHP
  • Common AHP symptoms
  • How and why AHP can be easily misdiagnosed
  • Biochemical testing for AHP
  • Genetic testing
 
Patient burden of acute hepatic porphyria

Module 04:
The Patient Burden of Acute Hepatic Porphyria (AHP)

Patient burden of acute hepatic porphyria
 

Module 4 Reviews:

  • The clinical and lifestyle burden of AHP
  • Challenges with diagnosis
  • The debilitating physical and emotional effects AHP has on patients’ daily functioning
 
Acute hepatic porphyria diagnosis and testing handout

AHP Diagnosis and
Testing Handout

Acute hepatic porphyria diagnosis and testing handout

This helpful flyer summarizes:

  • What AHP is
  • The signs and symptoms
  • Misdiagnosis
  • Testing using random (spot) urine
  • Consequences of delayed diagnosis
 
Acute hepatic porphyria random urine testing guide

AHP Random Urine
Testing Guide

Acute hepatic porphyria random urine testing guide

This detailed guide includes:

  • Testing and protocol information from major US laboratories
 

Access Additional Resources

For more information about AHP and other forms of porphyria, please visit American Porphyria Foundation and The Porphyrias Consortium. These organizations are dedicated to helping healthcare providers, patients, and their caregivers understand porphyria.